Thiopental Monitoring by Gas-Chromatography
نویسندگان
چکیده
منابع مشابه
Thiopental monitoring by gas-chromatography.
A gaschromatographic method is presented for the determination of thiopental (and of its metabolite pentobarbital) in cases of severe head injuries treated by induction of therapeutic barbiturate coma. To 1 ml serum the internal standard and saturated ammonium sulphate solution are added. The mixture is extracted by chloroform and the concentrated organic phase is injected into the gaschromatog...
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We describe an isothermal gas-liquid chromatographic procedure developed for measuring thiamylal and thiopental in plasma. The unchanged drug is extracted into ethyl acetate from acidified plasma, together with an internal standard. The solvent is removed, the residue methylated, aliquots, diluted with benzene, are injected into a 183-cm gas-liquid chromatographic column containing 3% OV-17. Se...
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We describe a comprehensive gas chromatographic analysis for therapeutic concentrations of amitriptyline, nortriptyline, imipramine, desipramine, doxepin, and desmethyldoxepin in plasma, with use of a nitrogen detector. All these drugs are extracted and chromatographed under identical conditions. Each tertiary amine tricyclic is well resolved from its secondary amine metabolite on a mixed-phase...
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RECEIVED for review February 21, 1978. Accepted June 19, 1978. NMR spectra since two distinct peaks (6 -3.38, 3.78 ppm) caused by these protons are observed in CDCA vs. only one peak (6 -3.45 ppm) caused by the same protons in UDCA. T h e fingerprint region of the spectrum (6 1-2.5 ppm) and the relative position of the CIS methyl peak with respect to tha t of the doublet caused by the Cpl methy...
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Disopyramide is determined in serum by gas chromatography with a nitrogen-selective detector, by liquid chromatography, and by gas chromatography--mass spectrometry. Comparable results are obtained with the three techniques, with a within-run and between-run precision of 5 to 10% (coefficient of variation). Least-squares analysis of data on patients' sera, analyzed first by gas chromatography (...
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ژورنال
عنوان ژورنال: Clinical Chemistry and Laboratory Medicine
سال: 1983
ISSN: 1434-6621,1437-4331
DOI: 10.1515/cclm.1983.21.3.181